Abstract
We have applied Stereotactic Intratumoral Photodynamic Therapy using HPE and argon-dye laser for 20 malignant brain tumors of 16 cases. The 6 females and 9 males were from age of 22 to 77. The average age was 52.5 years old. There were 7 cases of glioblastoma (3 recurrence), 4 cases of astrocytoma grade III, 4 cases of metastatic brain tumors and 1 case of PNET. All tumors clearly showed a reduction in tumor volume 4 weeks after stereotactic PDT. In the case of 20.7cc or lower volume (85%,17 tumors), therapeutic effects was obtained for all of them. The largest tumor which showed complete disappearance on enhanced CT or MRI had a volume of 4.6cc.The data indicate that it is possible to consider stereotactic intratumoral PDT showing adequate therapeutic effects as an adjuvant therapy for malignant brain tumors.
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