Abstract
Argon dye laser (628nm) irradiation for lymph nodes of rats was performed with light doses of 75 J/cm at 80mW at 48 hours after administration of 5mg hematoporphyrin derivative/Kg. Histological changes of irradiated lymph nodes were observed at 6,24 hours, 2, 3, 5, 7, 10 and 14 days after laser irradiation. Lymph nodes were highly reactive to photodynamic therapy (PDT) with HPD. Necrosis of lymph nodes occurred maximally at 24 hours after PDT. However, structure of the lymph nodes was completely restored to the former condition by 7 days after light exposure.
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Schedule a callMore From: THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE
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