Abstract
We report on a 14-year-old girl presenting with an acute headache syndrome that developed after intake of contraceptive drug. Laboratory values showed a homozygous mutation of factor V Leiden and we treated her initially with heparin, then with coumadin. There were no complications during the course of treatment. Interestingly, the initial headache responded well to therapy with sumatriptan, so it is assumed as a first manifestaion of migraine and this delayed the actually diagnosis. Imaging studies showed extensive cerebral venous sinus thrombosis. However, the patient had no focal deficits.
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