Abstract

lected: cardiovascular disease, peripheral neuropathy, renal disease, retinopathy, cataract, hypoglycemia, ketoacidosis and adverse birth outcomes. CONCLUSIONS: Since 2003, 281 reports of 72 studies (including many large, observational studies) have been published. These reports have substantially increased the available evidence describing complications in T1DM patients. The DCCT/EDIC studies uniquely provide long-term follow-up (now more than 23 years) of patients managed using strategies that are reasonably representative of contemporary T1DM management.

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