Abstract

Obesity is a prevalent disease in Chile. The National Health Survey (NHS) presents general prevalence by disease, but not the association between diseases and Body Mass Index (BMI). The conditional prevalence of BMI for cardiovascular, kidney, and liver diseases and their attributable risk percent (AR%) were estimated to obtain local clinical inputs for economic evaluations. The NHS database was expanded to 14.519.582 observations, using the multiplicative inverse for the general probability of selecting a person-k in a dwelling-j in the i-th block of a commune-c of a stratum-h. The general prevalence of each nutritional status, comorbidities conditional to BMI and their AR% are estimated utilizing STATA IC 14.2 and R.STUDIO. Results are presented by disease and nutritional status subgroups. The estimated prevalence for normal weight (NW), overweight (OW), grade I obesity (GIO) and grade 2 obesity (GIIO) were 24.35% (3,519,797), 39.83% (5,757,986), 23.39% (3,381,767) and 7.9% (1,142,556), respectively. For high blood pressure (HBP) prevalence was 11.5% (NW), 25% (OW), 29.6% (GIO), and 47% (GIIO). For type II diabetes (T2D), the prevalence by NW was 4.6%, 9.3% for OW, 14.2% for GIO, and 23% for GIIO. For chronic kidney disease (CKD) prevalence was 1.53% (NW), 1.52% (OW), 1.49% (GIO), and 2.98% (GIIO). The prevalence of cholelithiasis by NW was 11.45%, 25.11% (OW), 32.07% (GIO), and 36% (GIIO). For HBP, an AR% of 69.64% is obtained for GIIO (p-value<0.001). For GIIO, an AR% of 52.21% was calculated for acute myocardial infarction (p-value=0.001). In T2D, an AR% of 74.89% is obtained for GIIO (p-value<0.001). For cholelithiasis, an AR% of 54.97% (p-value<0.001), and 43.19% is obtained in the same subgroup (GIIO) for CDK (p-value=0.084). The AR% demonstrates the higher the BMI, the higher comorbidities. This database's statistical analysis provides new metadata for conducting local economic modeling by solving the gap of clinical inputs.

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