PD57-09 THE IMPORTANCE OF MRI-TARGETED BIOPSY FOR TUMORS IN ANTERIOR FIBROMUSCULAR STROMA

Abstract

You have accessJournal of UrologyCME1 May 2022PD57-09 THE IMPORTANCE OF MRI-TARGETED BIOPSY FOR TUMORS IN ANTERIOR FIBROMUSCULAR STROMA Hayato Yamamoto, Teppei Okamoto, Toru Yoneyama, and Chikara Ohyama Hayato YamamotoHayato Yamamoto More articles by this author , Teppei OkamotoTeppei Okamoto More articles by this author , Toru YoneyamaToru Yoneyama More articles by this author , and Chikara OhyamaChikara Ohyama More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002637.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Anterior prostate cancers are frequently missed since they can be neither palpable nor tangible on physical examination. The objective of this study was to analyze the MRI/transrectal ultrasound-fusion biopsies to detect and to characterize significant prostate cancer in the anterior fibromuscular stroma (AFS) and in the transition zone of the prostate. METHODS: One hundred and fourteen patients underwent prebiopsy 3 T multi parametric (mp) MRI and transperineal biopsy between February 2019 and May 2021. MRI images were analyzed using PIRADS (Prostate Imaging-Reporting and Data System) ver 2. All patients had systematic biopsies and targeted biopsies with rigid software registration in case of MRI-suspicious lesions. RESULTS: The positive rates of systematic and targeted biopsies were 10% and 29%, respectively with a significant difference. The cancer occupancy rate of the biopsy specimens was higher in the targeted biopsy, 22.2% and 36.3%, respectively. There were AFS tumors in 23 of 114 patients, and they harbored 23 lesions (10%) in AFS on mpMRI. The positive rate of targeted biopsy by PI-RADs category was 77% for PI-RADs 5, 42% for PI-RADs 4, and 16% for PI-RADs 3. The positive rate by target region were 24%, 31%, and 83% for peripheral zone (PZ), transition zone (TZ), and AFS, respectively. Especially, in PIRADs category 3 region, the positive rate in AFS region was a high positivity rate of 100%. CONCLUSIONS: Targeted biopsy has improved cancer detection rates. However, we should also pay attention to lesions of low PIRADs category in the AFS region. Source of Funding: none © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e964 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Hayato Yamamoto More articles by this author Teppei Okamoto More articles by this author Toru Yoneyama More articles by this author Chikara Ohyama More articles by this author Expand All Advertisement PDF DownloadLoading ...