PD5-02 MULTICENTER EXPERIENCE OF A NOVEL TREATMENT FOR BPH: AQUABLATION – IMAGE GUIDED ROBOT-ASSISTED WATER JET ABLATION OF THE PROSTATE

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II1 Apr 2015PD5-02 MULTICENTER EXPERIENCE OF A NOVEL TREATMENT FOR BPH: AQUABLATION – IMAGE GUIDED ROBOT-ASSISTED WATER JET ABLATION OF THE PROSTATE Peter Gilling, Andrew Tan, and Paul Anderson Peter GillingPeter Gilling More articles by this author , Andrew TanAndrew Tan More articles by this author , and Paul AndersonPaul Anderson More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.301AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To report the initial multicenter clinical experience in males with BPH undergoing ablation of the prostatic adenoma using an image-guided waterjet tissue ablation modality called Aquablation (PROCEPT BioRobotics, Redwood Shores, CA). METHODS The Aquablation System delivers a high-velocity saline stream (the AquaBeam®) under precise electromechanical control and live ultrasound guidance to ablate prostatic glandular tissue without the production of heat. Using the real-time transrectal ultrasound image and an integrated planning station, the target region for excision is registered within the prostate and the target tissue contour and depth are programmed by the surgeon. The surgeon guided AquaBeam ablates the prostatic tissue accurately following a preprogrammed routine, and the ablated prostatic tissue is simultaneously collected for post-procedure analysis. To obtain hemostasis if necessary, standard electro cautery is used. RESULTS 21 males with symptomatic BPH were enrolled and treated with Aquablation under general anesthesia. Monitored data are available on all 21 males treated. The mean age was 69.7 years (SD=5.1, 62–78) and baseline prostate size was 57g (SD=19.4, 30–102). Median lobe was present in 12 of the 21 subjects treated. All procedures were technically successful with a mean total operative time of 38 minutes (SD=9.0, 23–56) and Aquablation treatment time of 5.0 minutes (SD=2.9, 2–13). All patients were catheterized post-procedure and catheters were removed within 24 hours in 20/21 patients. Median catheterization time was 1 day. Hemoglobin at time of discharge reduced by 5.7% from 143.1 to 134.8 g/l from baseline. There were no procedure related cases of retrograde ejaculation, urinary incontinence or erectile dysfunction. Other peri-operative complications were comparable to those observed with other available BPH therapies. The Qmax improved from 8.6 – 21.7 ml/s, IPSS from 23 to 8.9, QoL from 5 – 2.6 and the PVR from 143 – 25 ml from baseline to 6 months with n=20 at baseline and 1 month, n=15 at 3 months and n=8 at 6 months. CONCLUSIONS Aquablation with ultrasound image-guidance is a promising technique delivering a personalized, quantifiable and standardized ablation of the enlarged prostate. Preliminary results from this multicenter experience are encouraging. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e92-e93 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Peter Gilling More articles by this author Andrew Tan More articles by this author Paul Anderson More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...