PD47-04 NATIVITY AND BLADDER CANCER OUTCOMES IN MULTI-ETHNIC POPULATIONS: A CALIFORNIA CANCER REGISTRY ANALYSIS

Abstract

You have accessJournal of UrologyBladder Cancer: Epidemiology & Evaluation II (PD47)1 Sep 2021PD47-04 NATIVITY AND BLADDER CANCER OUTCOMES IN MULTI-ETHNIC POPULATIONS: A CALIFORNIA CANCER REGISTRY ANALYSIS Sumeet Bhanvadia, Unwanaobong Nseyo, Sidney Roberts, Ziwei Song, Lihua Liu, Inderbir Gill, Siamak Daneshmand, and Mariana C. Stern Sumeet BhanvadiaSumeet Bhanvadia More articles by this author , Unwanaobong NseyoUnwanaobong Nseyo More articles by this author , Sidney RobertsSidney Roberts More articles by this author , Ziwei SongZiwei Song More articles by this author , Lihua LiuLihua Liu More articles by this author , Inderbir GillInderbir Gill More articles by this author , Siamak DaneshmandSiamak Daneshmand More articles by this author , and Mariana C. SternMariana C. Stern More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002069.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: While racial disparities in bladder cancer (BC) outcomes have been described, it is unclear to what degree foreign-born status contributes to disparities among racial/ethnic minorities. We investigated clinical characteristics and survival patterns for bladder cancer (BC) among various racial/ethnic groups, factoring in nativity as compared to non-Latino Whites (NLW). METHODS: We used data from the California Cancer Registry (1995-2017) to identify BC cases among California residents diagnosed between January 1, 1977 and December 31, 2017. Latino status and country of origin were identified by the NAACCR Hispanic Identification Algorithm (NHIA) and birthplace variable. Nativity (US-born versus foreign-born) was defined based on birthplace information. Cox regression modeling was performed to determine overall cancer-specific mortality (CSM) adjusting for sex, age, stage, treatment, SES, nativity and insurance type, using non-Latino white (NLW) as the reference. RESULTS: We identified a total of 141,083 cases of all stages/grades of BC: 113461 NLW (80.4%), 13,310 Latinos (9.4%), 8529 Asians (6.0%), and 5783 non-Latino Blacks (NLB) (4.1%). Foreign-born (FB) Asians and Latinos represented 81.1% and 52.6% of their total populations, respectively. Relative to NLW, Latinos and Asians had worse clinical characteristics in terms of higher stage at presentation, tumor size, and longer time interval before treatment. FB members of both racial/’ethnic groups were more likely to be of low SES, uninsured, married, and older at diagnosis. FB Asians had higher rates of nodal and metastatic disease at presentation compared to US-born Asians. While FB Latinos (10.3%) presented at a higher stage relative to US Latinos (9.1%), there was a greater frequency of FB Latinos receiving no treatment. On adjusted regression analysis, US Latinos had the highest risk of dying of BC and FB individuals fared better than their US-born counterparts. CONCLUSIONS: Differences in BC incidence, treatment patterns and surgical outcomes were observed between FB and US-born populations among Latinos and Asians. Despite higher prevalence of adverse characteristics among FB Latinos, US-born Latinos had the worst survival outcomes. This study highlights the need for more in-depth study of outcomes within racial/ethnic subgroups. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e833-e834 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sumeet Bhanvadia More articles by this author Unwanaobong Nseyo More articles by this author Sidney Roberts More articles by this author Ziwei Song More articles by this author Lihua Liu More articles by this author Inderbir Gill More articles by this author Siamak Daneshmand More articles by this author Mariana C. Stern More articles by this author Expand All Advertisement Loading ...