PD47-03 RELATIONSHIP BETWEEN SPONTANEOUS PASSAGE RATES OF URETERAL STONES LESS THAN 10 MM AND SERUM C-REACTIVE PROTEIN LEVEL AND NEUTROPHIL PERCENTAGE

Abstract

INTRODUCTION AND OBJECTIVES: conservative management of ureteral stones may fail after the patient had experienced several bouts of the severe renal colic, with the added problems of the cost and side effects of the drugs. So, an invasive treatment would have been better to start with. Therefore, we investigated the role of Creactive protein (CRP) level and Neutrophil percentage as predictive factors of ureteral stone passage. METHODS: One hundred and forteen patients treated by conservative treatment for ureteric stones, were prospectively divided into two groups according to stone size (less than 10 and less than 5 mm). According to serum C-reactive protein, patients were divided into three subgroups, with normal serum CRP levels of (0 4.9) mg/dL, mild elevation (59.9) mg/dL, and high elevation (over 10) mg/dL. According to serum neutrophil patients were divided into two subgroups, with normal neutrophil percentages of (38-74%) and a group with higher neutrophil percentages (>74%). RESULTS: Although the stone size was the major predicting factor for stone passage, the study demonstrated a significant relationship between spontaneous passage rates of ureteral stones and serumC reactive protein levels and neutrophil percentage. This study showed that ureteral stone passage rates of the low serum CRP level group, the medium serum CRP level group, and the high serum CRP level group were 80.0% (48/60), 62.1% (18/29), and 44.0% (11/25), respectively. The passage rates of ureteral stones in the group with a normal neutrophil percentage and in the group with a higher neutrophil percentage were 50.0% (21/42) and 77.8% (56/72), respectively (p1⁄40.011). CONCLUSIONS: CRP and neutrophil percentage could be added to the diagnostic armamentarium of ureteral stone disease and could be considered as one of the factors that the urologist may rely on when recommending treatment to patients with ureteral calculi