Abstract

Aim Asthma is a chronic disease of the lower respiratory tract that is characterized by inflammation and bronchial obstruction. The pathophysiology of the disease is related to constriction of the bronchial smooth muscle, something that is influenced by calcium homeostasis. Important role in calcium homeostasis, play various binding proteins, which belongs to the family of proteins S100 (S100). The purpose of this study was to measure S100 protein in a group of children with bronchial asthma (BA) in comparison with age-sex matched control group.

Highlights

  • 10 patients and 10 age-sex matched controls were included in our study; Patients with acute infection were excluded from this study in order to avoid blases that could lead to misinterpretation

  • The pathophysiology of the disease is related to constriction of the bronchial smooth muscle, something that is influenced by calcium homeostasis

  • Important role in calcium homeostasis, play various binding proteins, which belongs to the family of proteins S100 (S100)

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Summary

Introduction

10 patients (mean age 8±4.6, 6♂ and 4♀) and 10 age-sex matched controls (mean age 7.4±3.1, 4♂ and 6♀) were included in our study; Patients with acute infection were excluded from this study in order to avoid blases that could lead to misinterpretation. PD46 - Serum level of S 100 proteins in patients with asthma Theodora Gioka1, Theocharis Konstantinidis1, Christina Tsigalou1, Eleni Hatziioannou1, Georgia Kampouromiti1, Dimitrios Cassimos2* From 3rd Pediatric Allergy and Asthma Meeting (PAAM) Athens, Greece.

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