PD44-12 POSITIVE ASSOCIATION BETWEEN LOWER URINARY TRACT SYMPTOMS AND COITAL URINARY INCONTINENCE IN NULLIPAROUS WOMEN

Abstract

INTRODUCTION AND OBJECTIVE: Coital urinary incontinence (CUI) is a clinical problem with significant impact on quality of life, yet continues to be infrequently studied and underdiagnosed. CUI has been shown to have a prevalence of 10-66% in women with urinary incontinence but it has not been well-studied in a nulliparous population, where the presence of CUI may be particularly distressing. The objective of our study was to examine the association of CUI and other lower urinary tract symptoms (LUTS) in nulliparous women (NW). METHODS: An IRB approved, cross-sectional electronic survey was administered to women ≥ 18 years old with a secondary analysis aimed to evaluate the association between LUTS and CUI. We included all non-pregnant, nulliparous, female participants who completed the survey. Using responses to validated questionnaires including the ICIQ-FLUTS, we queried the prevalence of urgency, urgency urinary incontinence (UUI), stress urinary incontinence (SUI), overactive bladder (OAB), and CUI. Descriptive summary statistics were tabulated and Chi-squared tests were used to identify associations. RESULTS: Our cohort included 1,533 NW, of which 121(7.9%) reported CUI. The mean age was 31.2 years (SD 10.9) and mean BMI 24.7 (SD 5.5). There were no significant differences in age, BMI, race, education, smoking, or hysterectomy status between NW with and without CUI. In NW women with diabetes, 21.05% reported CUI, compared to 7.56% of NW without diabetes (p=0.002). Compared to NP without CUI, NP with CUI were more likely to have stress urinary incontinence (10.91% vs 39.67%, p<0.001), urge urinary incontinence (8.36% vs 23.97%, p<0.001), overactive bladder (18.27% vs 42.15%, p<0.001), and urinary urgency (14.80% vs 32.23%, p<0.001). CONCLUSIONS: A low but significant percentage of nulliparous women experience CUI. The presence of LUTS with or without incontinence in NP was found to have a strong positive association with CUI. Further research is needed in this population in order to identify the degree of bother and treatment strategies for CUI in order to better address this under-diagnosed condition.Source of Funding: CTSA award No. UL1 TR002243 from the National Center for Advancing Translational Sciences