Abstract

INTRODUCTION AND OBJECTIVES: Minimally invasive approaches to adrenal surgery are widely utilized in an attempt to reduce surgical morbidity. Despite widespread use, few studies objectively evaluate Health Related Quality of Life (HRQOL) in patients undergoing laparoscopic adrenalectomy. We assessed health status and recovery after laparoscopic adrenalectomy with the use of validated patientreported outcome questionnaires. METHODS: We enrolled patients scheduled to undergo adrenal surgery at our institution in an IRB-approved, prospective, longitudinal quality of life study. Informed consent was obtained for all subjects. We administered HRQOL questionnaires at pre-treatment baseline, and at 2, 4, 8, 12 and 52 weeks after surgery. We assessed surgical convalescence using Convalescence And Recovery Evaluation (CARE), an abdominal/pelvic surgery questionnaire, and general HRQOL with the Short Form 12 (SF-12) instrument. RESULTS: We analyzed 26 patients who underwent laparoscopic adrenalectomy since 2009. Patient characteristics are described in Table 1. Quality of life reflected by the CARE survey was most significantly reduced at 2 weeks postoperative (-14.82) and had returned to baseline by 4 weeks (Figure). Second week pain, gastrointestinal and activity domains of CARE showed significant average decrease from baseline (-17.01, -5.17, -36.61 respectively). Significant decrease in the physical component summary of the SF-12 questionnaire at 2 and 4 weeks reflected the impact of surgery on activity level during the first 4 weeks of recovery. CONCLUSIONS: Despite a minimally invasive approach, surgery-related pain in the first two weeks after laparoscopic adrenalectomy may significantly limit patients’ physical activity and may extend complete convalescence up to 4 weeks. Patient demographics and characteristics

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