PD37-11 LONG-TERM URINARY AND SEXUAL OUTCOMES IN PEDIATRIC GENITOURINARY RHAMDOMYOSARCOMA SURVIVORS: A QUALITATIVE STUDY

Abstract

You have accessJournal of UrologyCME1 Apr 2023PD37-11 LONG-TERM URINARY AND SEXUAL OUTCOMES IN PEDIATRIC GENITOURINARY RHAMDOMYOSARCOMA SURVIVORS: A QUALITATIVE STUDY Christopher Jaeger, Andrea Balthazar, Rachel Saunders, Monah Javidan-Nejad, Candace Chung, Judith Vessey, Richard Lee, and Hsin-Hsiao Wang Christopher JaegerChristopher Jaeger More articles by this author , Andrea BalthazarAndrea Balthazar More articles by this author , Rachel SaundersRachel Saunders More articles by this author , Monah Javidan-NejadMonah Javidan-Nejad More articles by this author , Candace ChungCandace Chung More articles by this author , Judith VesseyJudith Vessey More articles by this author , Richard LeeRichard Lee More articles by this author , and Hsin-Hsiao WangHsin-Hsiao Wang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003335.11AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Genitourinary Rhabdomyosarcoma (GU-RMS) often requires multimodal therapy including radiation, chemotherapy, and radical surgery to maximize disease control. The long-term effects of the disease and associated treatments are unclear. We sought to investigate the long-term genitourinary quality of life (QoL) for adult survivors of pediatric GU-RMS, including urinary function, fertility, sexual function, and associated QoL. METHODS: In total, 14 (43% female, median age=32.5 years [IQR=23.25–39.25], 2 bladder, 1 cervical, 5 paratesticular, 3 vaginal, 2 pelvic, 1 prostate RMS) agreed to interview about impact of childhood GU-RMS treatment on current QoL. A semi-structured interview guide based on a Long-Term Service and Support QoL conception model (LTSS HRQOL), and grounded in GU-RMS experiences was created. Categories included urinary function, sexual function, general health, mental health, and social dynamics. Two coders independently coded using thematic analysis. RESULTS: Three themes specific to genitourinary functions emerged: fertility preservation, sexual health communication with partners, and education of GU-RMS impact during and after treatment. Participants discussed an interest in better understanding fertility preservation options, and post-treatment effects on their anatomy. They noted that knowledge of their ability to conceive impacted their desire to have children. Participants also had challenges related to if, when or how to communicate details of their sexual health with a partner. Across these themes, participants reported insufficient knowledge regarding GU-RMS treatment and its impact on current and future functions. Specific areas of concern were anatomical changes, fertility and pregnancy expectations, and survivorship. CONCLUSIONS: For survivors of GU-RMS, significant urinary and sexual function concerns would be important to address with long-term survivorship. Clinicians can potentially improve survivors’ QoL by educating on expectations for treatment, fertility preservation options, and long-term effects of treatment, at relevant stages in a patient’s life. Source of Funding: Internal © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e992 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Christopher Jaeger More articles by this author Andrea Balthazar More articles by this author Rachel Saunders More articles by this author Monah Javidan-Nejad More articles by this author Candace Chung More articles by this author Judith Vessey More articles by this author Richard Lee More articles by this author Hsin-Hsiao Wang More articles by this author Expand All Advertisement PDF downloadLoading ...