Abstract
Atopic dermatitis is a chronic inflammatory disorder of the skin, charachterised by a TH2 skewed cytokine profile, usually elevated total serum IgE and can be co coexpressed with other atopic clinical manifestations. The atopic skin is prone to bacterial colonization and that has an effect on immunological parameters. Atopic Dermatitis has been correlated with IgG hypoglobulinaemia, low serum IgA and downregulation of the CD8 lymphocytes in peripheral blood.
Highlights
Atopic dermatitis is a chronic inflammatory disorder of the skin, charachterised by a TH2 skewed cytokine profile, usually elevated total serum IgE and can be co coexpressed with other atopic clinical manifestations
Atopic Dermatitis has been correlated with IgG hypoglobulinaemia, low serum IgA and downregulation of the CD8 lymphocytes in peripheral blood
Scope The aim of the study was to evaluate intracellular Th1 and Th2 cytokines secreted by CD3 T cells in children with Atopic Dermatitis, irrespectively of the coexpression of other atopic manifestations and their correlation with other immunological parameters regarding innate and adaptive immunity
Summary
PD36 - Evaluation of intracellular cytokines IL-2, IFNg, IL-4 and IL-5 in children with atopic dermatitis and correlations with other immunological and epidemiological parameters. Maria Koulouri1*, Efie Vrachnou, Emmanouil Liatsis, Andreas Konstantopoulos, Maria Kanariou. From 3rd Pediatric Allergy and Asthma Meeting (PAAM) Athens, Greece. From 3rd Pediatric Allergy and Asthma Meeting (PAAM) Athens, Greece. 17-19 October 2013
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