PD33-10 NEPHROMETRY AND CUMULATIVE MORBIDITY AFTER PARTIAL NEPHRECTOMY: A STANDARDIZED ASSESSMENT OF COMPLICATIONS IN THE CONTEXT OF R.E.N.A.L. AND PADUA SCORES

Abstract

You have accessJournal of UrologyCME1 May 2022PD33-10 NEPHROMETRY AND CUMULATIVE MORBIDITY AFTER PARTIAL NEPHRECTOMY: A STANDARDIZED ASSESSMENT OF COMPLICATIONS IN THE CONTEXT OF R.E.N.A.L. AND PADUA SCORES Dejan K. Filipas, Hang Yu, Clemens Spink, Michael Rink, Silke Riechardt, Philipp Gild, Phillip Marks, Margit Fisch, Roland Dahlem, Christian P. Meyer, and Malte W. Vetterlein Dejan K. FilipasDejan K. Filipas More articles by this author , Hang YuHang Yu More articles by this author , Clemens SpinkClemens Spink More articles by this author , Michael RinkMichael Rink More articles by this author , Silke RiechardtSilke Riechardt More articles by this author , Philipp GildPhilipp Gild More articles by this author , Phillip MarksPhillip Marks More articles by this author , Margit FischMargit Fisch More articles by this author , Roland DahlemRoland Dahlem More articles by this author , Christian P. MeyerChristian P. Meyer More articles by this author , and Malte W. VetterleinMalte W. Vetterlein More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002584.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Nephrometry scores aid in clinical decision-making and improve preoperative risk assessment in patients with renal masses scheduled for surgery. However, there is a lack of knowledge whether nephrometry scores are correlated with cumulative morbidity after partial nephrectomy (PN). We aimed to evaluate the association of PADUA and R.E.N.A.L. scores with the 30-d Comprehensive Complication Index (CCI®) after PN for renal masses. METHODS: Patients undergoing PN between 01/2019-08/2020 with preoperative imaging were included. R.E.N.A.L. and PADUA scores were calculated for each patient and 30-d complications were extracted from digital charts according to both a procedure-specific predefined catalog and the EAU Guidelines on Reporting and Grading of Complications. Pearson correlation was performed to evaluate the relationship between R.E.N.A.L/PADUA scores with the CCI®, which reflects cumulative morbidity on a scale from 0-100 and is based on the validated Clavien-Dindo classification. RESULTS: Of 122 patients, 101 (83%) underwent open and 21 (17%) robot-assisted PN for renal cell carcinoma, benign lesions, or other malignancies in 85 (70%), 29 (24%), and 8 (6.6) of the cases, respectively. Median PADUA and R.E.N.A.L. scores were 9 (IQR 8-10) and 8 (IQR 6-9), respectively. Overall, 218 complications were captured in 92 patients (75%), of which 95% were classified as Clavien-Dindo ≤IIIa. Overall median CCI® was 8.7 (IQR 0.50-15). In PADUA low (score 6-7), moderate (score 8-9), and high complexity (score 10-14) groups there was a difference in median CCI® (8.7 vs. 8.7 vs. 12; p=0.002), which was not confirmed for R.E.N.A.L low (score 4-6), moderate (score 7-9), and high complexity (score 10-12) groups (8.7 vs. 12 vs. 10; p=0.074). There was a small positive correlation between PADUA or R.E.N.A.L. score with CCI® (Figure 1), explaining only 4.7% and 4.1% of the variation in CCI®, respectively. CONCLUSIONS: In a tertiary referral center, PN can be safely performed with low short-term morbidity. Increasing tumor complexity as measured by validated nephrometry scores does not negatively impact perioperative complications when employing a standardized complication assessment and using the novel CCI® to capture comprehensive, cumulative morbidity. Source of Funding: n/a © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e556 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Dejan K. Filipas More articles by this author Hang Yu More articles by this author Clemens Spink More articles by this author Michael Rink More articles by this author Silke Riechardt More articles by this author Philipp Gild More articles by this author Phillip Marks More articles by this author Margit Fisch More articles by this author Roland Dahlem More articles by this author Christian P. Meyer More articles by this author Malte W. Vetterlein More articles by this author Expand All Advertisement PDF DownloadLoading ...