Abstract
INTRODUCTION: Every tissue in the body contains some type of stem or progenitor cells. These cells are believed to be part of underlying regenerative machinery that is responsible for daily maintenance and repair of injured tissue. In this study, we aimed to regenerate muscle functionality following volumetric muscle loss through the use of a target-specific scaffolding system. The objectives of this study were to evaluate the functionalized decellularized tissue scaffolds on the host muscle cell migration and muscle function recovery in vivo.
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