PD3-02 CADAVERIC ORGAN-SPECIFIC ACELLULAR MATRIX FOR URETHRAL RECONSTRUCTION IN HUMANS: LONG TERM RESULTS

Abstract

(41, 52.6%), LS (31, 39.7%), a combination of both (3, 3.8%), trauma (4, 5.1%) or idiopathic recurrent stricture (4, 5.5%).Multifocal or panurethral stricture requiring simultaneous single stage repair of the bulbar urethra was present in 29 (37.2%). Disease was limited to the penile urethra in 49 (62.8%). Bilateral buccal graftswere required in 35 (44.9%) cases. To date 74 (94.9%) have been tubularized while 3 (3.8%) are pending second stage for various medical and socioeconomic reasons, 1 (1.3%) received his second stage elsewhere, and 1 (1.3%) opted to remain with a penoscrotal urethrotomy. Mean follow upwas 11.9months ( 0.75-104) and 50 (64.1%) had follow up of greater than 3 months. There were 14 complications in 12 (15.4%) patients with an overall complication rate of 17.9%. Eight (10.3%) patients required revision with 2 patients requiring multiple revisions. Details are as per Table 1. CONCLUSIONS: Staged BMG urethroplasty is often necessary to successfully manage complex and long-segment anterior urethral strictures in the setting of LS or previous hypospadias repair. Our series demonstrates a very high rate of long term urethral patency and follow-through with urethral re-tubularization which is not evident in other series. Follow-up rates reflect the tertiary referral pattern. Complication and revision rates are low, and most frequently involve manageable distal urethrocutaneous fistula or glanular dehiscence.