PD30-07 ADHERENCE TO EUROPEAN ASSOCIATION OF UROLOGY GUIDELINE RECOMMENDATION FOR PELVIC LYMPH NODE DISSECTION IN AN EUROPEAN HIGH-VOLUME CENTER

Abstract

You have accessJournal of UrologyProstate Cancer: Localized II1 Apr 2015PD30-07 ADHERENCE TO EUROPEAN ASSOCIATION OF UROLOGY GUIDELINE RECOMMENDATION FOR PELVIC LYMPH NODE DISSECTION IN AN EUROPEAN HIGH-VOLUME CENTER Sami-Ramzi Leyh-Bannurah, Jonas Schiffman, Alexander Haese, Georg Salomon, Thomas Steuber, Thorsten Schlomm, Burkhard Beyer, Uwe Michl, Hans Heinzer, Hartwig Huland, Markus Graefen, Lars Budäus, and Pierre Karakiewicz Sami-Ramzi Leyh-BannurahSami-Ramzi Leyh-Bannurah More articles by this author , Jonas SchiffmanJonas Schiffman More articles by this author , Alexander HaeseAlexander Haese More articles by this author , Georg SalomonGeorg Salomon More articles by this author , Thomas SteuberThomas Steuber More articles by this author , Thorsten SchlommThorsten Schlomm More articles by this author , Burkhard BeyerBurkhard Beyer More articles by this author , Uwe MichlUwe Michl More articles by this author , Hans HeinzerHans Heinzer More articles by this author , Hartwig HulandHartwig Huland More articles by this author , Markus GraefenMarkus Graefen More articles by this author , Lars BudäusLars Budäus More articles by this author , and Pierre KarakiewiczPierre Karakiewicz More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1828AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Contemporary adherence to European Association of Urology (EAU) guideline recommendation for pelvic lymph node dissection (PLND) at either open (ORP) or robot-assisted radical prostatectomy (RARP) in an European high-volume center is unknown. To assess guideline recommended and observed PLND rates at ORP or RARP in a high-volume center cohort. METHODS We relied on a large European institutional database and focused on localized prostate cancer (PCa) patients, who were treated with either ORP or RARP, between 2010 and 2013. Categorical and multivariable logistic regression analyses targeted two endpoints: 1) probability of guideline recommended PLND and 2) probability of no PLND, when not recommended by EAU guidelines. RESULTS Within 7,868 PCa patients, adherence to EAU PLND guideline recommendation was 97.1% at ORP and 96.8% at RARP. When PLND was not recommended, it was more frequently performed at RARP (71.6%) than at ORP (66.2%). At recommended PLND, 21.1% of ORP patients harbored lymph node invasion (LNI) (number needed to treat (NNT): 4.7) vs. 9.9% RARP (NNT: 10.1). At not recommended PLND, 2.9% of ORP patients harbored LNI (NNT: 34.5) vs. 1.4% in RARP (NNT: 71.4). CONCLUSIONS Adherence to EAU guideline recommended PLND is high at this high-volume center. Neither ORP nor RARP represent a barrier for PLND, when recommended. However, a high number of patients underwent PLND despite absence of guideline recommendation. Possible staging advantages and PLND related complications needs to be individually considered, especially, when LNI risk is low. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e657 Peer Review Report Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sami-Ramzi Leyh-Bannurah More articles by this author Jonas Schiffman More articles by this author Alexander Haese More articles by this author Georg Salomon More articles by this author Thomas Steuber More articles by this author Thorsten Schlomm More articles by this author Burkhard Beyer More articles by this author Uwe Michl More articles by this author Hans Heinzer More articles by this author Hartwig Huland More articles by this author Markus Graefen More articles by this author Lars Budäus More articles by this author Pierre Karakiewicz More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...