PD29-10 VALIDATED ASSESSMENT OF URINARY, SEXUAL AND GASTROINTESTINAL QUALITY OF LIFE AFTER ROBOTIC ASSISTED LAPAROSCOPIC PROSTATECTOMY: BEYOND CONTINENCE AND ERECTIONS

Abstract

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy IV1 Apr 2018PD29-10 VALIDATED ASSESSMENT OF URINARY, SEXUAL AND GASTROINTESTINAL QUALITY OF LIFE AFTER ROBOTIC ASSISTED LAPAROSCOPIC PROSTATECTOMY: BEYOND CONTINENCE AND ERECTIONS Simone Albisinni, Fouad Aoun, Quentin Marcelis, Mehdi Idrissi, Thierry Quackels, Ksenija Limani, Eric Hawaux, Alexandre Peltier, Roland van Velthoven, and Thierry Roumeguère Simone AlbisinniSimone Albisinni More articles by this author , Fouad AounFouad Aoun More articles by this author , Quentin MarcelisQuentin Marcelis More articles by this author , Mehdi IdrissiMehdi Idrissi More articles by this author , Thierry QuackelsThierry Quackels More articles by this author , Ksenija LimaniKsenija Limani More articles by this author , Eric HawauxEric Hawaux More articles by this author , Alexandre PeltierAlexandre Peltier More articles by this author , Roland van VelthovenRoland van Velthoven More articles by this author , and Thierry RoumeguèreThierry Roumeguère More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.1385AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Continence and erectile function represent major concerns for patients and surgeons after robotic assisted laparoscopic prostatectomy (RALP), although the analysis of only these results may underestimate the true impact of surgery on Quality of Life (QoL). Aim of the study is to prospectively analyze QoL after RALP according to the validated EORTC-QLQ-PR25. METHODS 584 patients undergoing RALP in two academic institutions were prospectively enrolled. QoL was assessed via the EORTC-QLQ-PR25, composed of 25 questions analyzing QoL according to urinary symptoms, bother from incontinence aid, bowel symptoms, treatment related symptoms, sexual activity and sexual function, and expressed as percentages. Moreover, patients reported continence status via ICIQ and erectile function via IIEF5. Differences across QoL items was assessed by Wilcoxon rank sum test and association between risk factors and QoL scores was tested via uni and multivariate linear regressions. RESULTS Overall, all items of PR25 questionnaire showed a significant deterioration 1mo after RALP and began to normalize after 3mo. At 24 months, urinary, bowel and sexual activity QoL were not significantly different from preoperative scores, while incontinence aid, treatment-related symptoms and sexual functioning remained significantly worse. On multivariate analysis, patients with non-specimen confined disease (>pT3a or pN1 or positive margin) had a significantly higher risk of worse bowel and treatment related symptoms. Preoperative sexual activity was more important in determining 3mo sexual outcomes than preoperative IIEF5 or nerve sparing approach. 2 years after surgery, age, preoperative sexual activity and sexual functioning were the most significant predictors of sex related QoL. CONCLUSIONS In this prospective study, we report detailed data on QoL via the EORTC PR25 questionnaire. While urinary, bowel and sexual activity scores return to baseline values 24 months after surgery, incontinence-aid, treatment related symptoms and sexual functioning may remain significantly deteriorated. Moreover, patients’ age and preoperative erectile function appear to be more significant than nerve sparing and IIEF5 score in determining postoperative sex related QoL © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e571-e572 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Simone Albisinni More articles by this author Fouad Aoun More articles by this author Quentin Marcelis More articles by this author Mehdi Idrissi More articles by this author Thierry Quackels More articles by this author Ksenija Limani More articles by this author Eric Hawaux More articles by this author Alexandre Peltier More articles by this author Roland van Velthoven More articles by this author Thierry Roumeguère More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...