PD29-02 RISK OF HYPERTENSION AFTER RENAL TRAUMA

Abstract

You have accessJournal of UrologyCME1 May 2022PD29-02 RISK OF HYPERTENSION AFTER RENAL TRAUMA Matthew S. Swallow, Odinachi I. Moghalu, Joshua J. Horns, Benjamin J. McCormick, and Jeremy B. Myers Matthew S. SwallowMatthew S. Swallow More articles by this author , Odinachi I. MoghaluOdinachi I. Moghalu More articles by this author , Joshua J. HornsJoshua J. Horns More articles by this author , Benjamin J. McCormickBenjamin J. McCormick More articles by this author , and Jeremy B. MyersJeremy B. Myers More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002577.02AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The risk of hypertension after renal trauma (RT) is not well-defined. Previous studies are limited by small cohorts and/or difficulty in long-term follow up after trauma. We aimed to utilize the Truven Health MarketScan (MS) database to evaluate the risk of hypertension after RT. METHODS: We conducted a retrospective analysis of inpatient records in MS from 2008-2017 for patients with renal and bladder/urethral trauma. Patients with a diagnosis of RT or non-renal lower genitourinary trauma (GUnRT) (bladder/urethral trauma) were identified through ICD-9/10 codes. The development of HTN (also defined by ICD-9/10 codes) was compared between those who experienced RT and a control group of those who experienced GUnRT. Patients were excluded if they experienced both trauma types, had pre-existing HTN, had less than one year of enrollment data prior to trauma, or if they were under 18 years of age. An adjusted analysis included multiple covariates. RESULTS: There were a total of 6,542 RT patients and 5,144 GUnRT patients. The median age was 52 years (IQR 31-65) for RT patients and 49 years (IQR 38-64) for GUnRT patients. Median follow up data was 18 months (IQR 6-38) for RT patients and 21 months (IQR 7-42) for GUnRT patients. A total of 2,232 (34.1%) RT patients developed post-trauma HTN compared to 1,194 (23.2%) GUnRT patients. On multivariate analysis, risk of post-trauma HTN was higher in individuals with RT compared to GUnRT (hazard ratio 1.75, 95% CI 1.63-1.88, p<0.001). Other covariates associated with increased risk of post-trauma HTN included increasing age, female gender, increased Charlson Comorbidity Index, increased inpatient length of stay, and presence of one or more of the following comorbidities: smoking, diabetes, obesity, hyperlipidemia, and alcohol use. Undergoing either an open or minimally invasive kidney procedure was not associated with a higher rate of HTN (hazard ratio 1.095, 95% CI 0.94-1.27, p=0.239). CONCLUSIONS: Patients experiencing renal trauma have an associated higher rate of developing hypertension compared to a control population. Patient age, female gender, and medical history of diabetes, obesity, and hyperlipidemia was also associated with increased risk of post-trauma HTN. Source of Funding: University of Utah Division of Urology © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e504 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Matthew S. Swallow More articles by this author Odinachi I. Moghalu More articles by this author Joshua J. Horns More articles by this author Benjamin J. McCormick More articles by this author Jeremy B. Myers More articles by this author Expand All Advertisement PDF DownloadLoading ...