PD26-12 FLACCID PENILE ULTRASOUND: A NEW POTENTIAL TOOL TO PREDICT THE INDIVIDUAL 10-YEAR RISK OF CARDIOVASCULAR DISEASE

Abstract

You have accessJournal of UrologyCME1 Apr 2023PD26-12 FLACCID PENILE ULTRASOUND: A NEW POTENTIAL TOOL TO PREDICT THE INDIVIDUAL 10-YEAR RISK OF CARDIOVASCULAR DISEASE Giovanni Cochetti, Giuseppe Maiolino, Michele Del Zingaro, Alessio Paladini, Graziano Felici, Giulia Manfredini, Angelica Tancredi, and Ettore Mearini Giovanni CochettiGiovanni Cochetti More articles by this author , Giuseppe MaiolinoGiuseppe Maiolino More articles by this author , Michele Del ZingaroMichele Del Zingaro More articles by this author , Alessio PaladiniAlessio Paladini More articles by this author , Graziano FeliciGraziano Felici More articles by this author , Giulia ManfrediniGiulia Manfredini More articles by this author , Angelica TancrediAngelica Tancredi More articles by this author , and Ettore MeariniEttore Mearini More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003304.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Cardiovascular risk has become a hot topic in evaluation of patients with vasculogenic erectile dysfunction (ED). Recently, European Society of Cardiology (ESC) designed a cardiovascular disease (CVD) Risk Calculation App to calculate individual 10-year risk of CVD for healthcare professionals based on specific population-target scores. Aim of our study is to evaluate the association between mean basal peak systolic velocity of cavernosal arteries and the 10-year risk in men with vasculogenic ED. METHODS: We prospectively evaluated all patients with vasculogenic ED who underwent penile ultrasound between September 2021 and July 2022. All patients were examined in the same setting: quiet and warm room, one expert operator, sampling of basal PSV in the first third of cavernosal artery with an angle of doppler between 40-50° and calculation of mean basal PSV (mbPSV) between right and left cavernosal artery. Exclusion criteria were: neurological disease or spinal injury, psychogenic (clinical suspicious and/or Beck Inventory Scale ≥14) erectile disfunction. For each patient we calculated 10-year risk of CVD disease using SCORE2 for patients between 40 and 69 years without history of cardiovascular disease and diabetes mellitus, SMART score for patients with a history of cardiovascular disease and ADVANCE score for patients with diabetes mellitus. All risk scores were calculated by CVD Risk Calculation App of ESC. Ethical Committee approval has been obtained. RESULTS: We enrolled 80 consecutive patients. Mean age and BMI were 57,9 years and 26,8 Kg/m2, respectively. Median IIF-5 was 13,7. Average mbPSV and 10-year risk of CVD disease resulted 13,6 cm/sec (range: 5,3 -32,4 cm/sec) and 10,8% (range: 1,9-34%), respectively. We found an inverse and significant correlation between mbPSV and 10-year risk of CVD disease (r: -0.29; p: 0,02). The correlation resulted significant in patients with a history of cardiovascular disease which were evaluated by SCORE2 (r: -0.34; p: 0,017) and a stronger significant inverse correlation was found between mbPSV and 10-year risk of CVD in patients with diabetes mellitus in which the cardiovascular risk was calculated by ADVANCE score (r: -0.61; p: 0,021). mbPSV resulted significantly correlated also with age (r: -0.28; p: 0,021). CONCLUSIONS: MbPSV is a useful screening tool in patients with vasculogenic ED to evaluate 10-year risk of cardiovascular (CVD) disease. A lower mbPSV is correlated with a higher cardiovascular risk, especially in patients with diabetes mellitus where risk is calculated by ADVANCE score. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e739 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Giovanni Cochetti More articles by this author Giuseppe Maiolino More articles by this author Michele Del Zingaro More articles by this author Alessio Paladini More articles by this author Graziano Felici More articles by this author Giulia Manfredini More articles by this author Angelica Tancredi More articles by this author Ettore Mearini More articles by this author Expand All Advertisement PDF downloadLoading ...