PD26-12 COMPLICATIONS ASSOCIATED WITH TRANSRECTAL AND TRANSPERINEAL PROSTATE MAPPING BIOPSY

Abstract

You have accessJournal of UrologyProstate Cancer: Detection & Screening VI1 Apr 2016PD26-12 COMPLICATIONS ASSOCIATED WITH TRANSRECTAL AND TRANSPERINEAL PROSTATE MAPPING BIOPSY Vassilios Skouteris, Nelson Stone, Paul Arangua, and E. David Crawford Vassilios SkouterisVassilios Skouteris More articles by this author , Nelson StoneNelson Stone More articles by this author , Paul AranguaPaul Arangua More articles by this author , and E. David CrawfordE. David Crawford More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.373AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To evaluate incidence of complications in men undergoing transrectal (TRUS) and transperineal mapping biopsy (TPMB). METHODS 366 men, of which 258 (70.5%), had a prior TRUS biopsy had TPMB performed through a template with biopsies taken at 5 mm intervals. Multiple in-line samples were taken if prostate length exceeded 2 cm. A proprietary software program was used to track biopsy locations. Men with prior TRUS had a median of 12 cores sampled while the 366 with TPMB had 51.5 cores. The number of cores taken was volume based. Associations between urinary infection and retention were compared in TRUS and TPMB with age, core number, prostate volume (PV), PSA, PSAD and prior TRUS biopsy number by ANOVA and chi-square. Multiple significant associations were compared by logistic regression. RESULTS Median Age, PSA and PSAD were 65 years, 5.5 mg/ml and 0.159. 218/366 (59.7%) were diagnosed with prostate cancer by TPMB with a median of 7.0 cores positive. 11/258 (4.3%) of the men who had TRUS biopsy developed urinary tract infections compared 3/336 (0.89%) of those with mapping biopsy. Age, number of TRUS biopsies (mean 1.5, range 1-9), or PV were not associated with TRUS infections. None of the 11 men with TRUS infections developed an infection after TPMB. Neither the number of cores taken by TPMB or a larger PV was associated with infection. 2 of the 3 men who developed infection after mapping also had post-TPMB urinary retention (OR 27.0, 95% CI 2.4-308.6, p<0.001). No TRUS biopsy men developed retention while 27/336 (7.4%) did following TPMB. Mean age, PV and core number was higher in retention patients (69.5 vs 64 years, p=0.001, 62.6 vs 46 cc, p<0.001 and 62.6 and 56.9 cores, p=0.011). PSA, PSAD, prior TRUS biopsy, number of prior TRUS biopsies and diagnosis of cancer was not associated with retention. Linear regression revealed age (p=0.001), PV (p=0.010) and number of cores (0.061) as significant. CONCLUSIONS Urinary tract infections are 5x more common in TRUS biopsy compared to TPMB. A TRUS biopsy followed by a mapping biopsy does not increase the risk of a urinary tract infection. Men who develop retention after TPMB are much more likely to develop an infection (7.4% vs 0.3%). Urinary retention occurred in 7.4% and was associated with older age and increased prostate size. These data should be helpful in counseling men who desire prostate biopsy by TPM. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e648-e649 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Vassilios Skouteris More articles by this author Nelson Stone More articles by this author Paul Arangua More articles by this author E. David Crawford More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...