PD26-06 GREENLIGHT XPS-180W LASER VAPORIZATION OF THE PROSTATE FOR BENIGN PROSTATIC HYPERPLASIA: A GLOBAL, MULTI-CENTER STUDY INCLUDING 1053 PATIENTS, ANALYSIS OF COMPLICATION RATES AND OUTCOMES AT 2 YEARS ACCORDING TO PROSTATE SIZE

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology I1 Apr 2014PD26-06 GREENLIGHT XPS-180W LASER VAPORIZATION OF THE PROSTATE FOR BENIGN PROSTATIC HYPERPLASIA: A GLOBAL, MULTI-CENTER STUDY INCLUDING 1053 PATIENTS, ANALYSIS OF COMPLICATION RATES AND OUTCOMES AT 2 YEARS ACCORDING TO PROSTATE SIZE Pierre-Alain Hueber, Marc Bienz, Daniel Liberman, Vincent Misrai, Matthew Rutman, Alexis E. Te, Bilal Chughtai, Richard Lee, Neil Barber, Amr M. Emara, Ricardo Gonzalez, and Kevin C. Zorn Pierre-Alain HueberPierre-Alain Hueber More articles by this author , Marc BienzMarc Bienz More articles by this author , Daniel LibermanDaniel Liberman More articles by this author , Vincent MisraiVincent Misrai More articles by this author , Matthew RutmanMatthew Rutman More articles by this author , Alexis E. TeAlexis E. Te More articles by this author , Bilal ChughtaiBilal Chughtai More articles by this author , Richard LeeRichard Lee More articles by this author , Neil BarberNeil Barber More articles by this author , Amr M. EmaraAmr M. Emara More articles by this author , Ricardo GonzalezRicardo Gonzalez More articles by this author , and Kevin C. ZornKevin C. Zorn More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.2093AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The aim of this study was to evaluate the safety and outcomes at 2 years of the new Greenlight XPS-180W laser system (AMS, Minnetonka, MI, USA) for the treatment of BPH in a large multicenter cohort. METHODS A total of 1053 patients underwent Greenlight laser photo-selective vaporization of the prostate for the treatment of BPH performed at 6 international centers between 2010 and 2012. Perioperative variables (International Prostate Symptom Score (IPSS), QoL, maximum flow rate (Qmax), post-void residual (PVR) and PSA levels were recorded at baseline, 3 and 6, 12 and 24 months post-operatively. The analysis of patients characteristics, operative parameters, complications and uroflowmetry outcomes was also stratified according to prostate volume >80 and <80cc. RESULTS Overall Mean (SD) patient age was 70.17 (9.23) years, with a mean PV of 74.54 cc (45.1) and PSA of 4.38 ng/ml (5). When stratified according to prostate size, all parameters (but BMI and QoL) including age (70.45 vs 67.36 years), PSA (5.8 vs 3.9 ng/ml), IPSS (22.5 vs 20.8), Qmax (6.1 vs 7.1ml/s) and PVR (267 vs 202 ml) were significantly different between prostate group size >80 cc compared to <80cc (p<0.001). In terms of complication, conversion to TURP was more prevalent in patients with larger glands (11.2% vs 1.1%; p<0.001). All other rates of complications including perforation (0.6% vs 0.6%), bleeding obscuring vision (3.8% vs 6.7%), bleeding hematuria (0.5 vs 0%) and blood transfusion (0.3% vs 0.5%) were relatively low and without significant difference between the two groups. Statistically, significant improvements compared to baseline were noted in all key clinical outcome parameters postoperatively at 3, 6, 12 and 24 months (p<0.05) without significant difference between the two groups (see figure). CONCLUSIONS XPS systems provide safe and effective tissue vaporization with significant clinical relief of BPH obstruction associated with objective outcomes and PSA reduction at 24 months confirming the mid-term durability of this procedure regardless of prostate size. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e761 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Pierre-Alain Hueber More articles by this author Marc Bienz More articles by this author Daniel Liberman More articles by this author Vincent Misrai More articles by this author Matthew Rutman More articles by this author Alexis E. Te More articles by this author Bilal Chughtai More articles by this author Richard Lee More articles by this author Neil Barber More articles by this author Amr M. Emara More articles by this author Ricardo Gonzalez More articles by this author Kevin C. Zorn More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...