PD20-10 HAVE ADVANCES IN PATIENT PREPARATION, SURGICAL TECHNIQUES, AND ANTIBIOTIC COATINGS REDUCED INFLATABLE PENILE PROSTHESIS PRIMARY IMPLANTATION INFECTION RATES TO NEARLY ZERO? A LARGE PROSPECTIVE MULTICENTER REGISTRY EXPERIENCE

Abstract

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Surgical Therapy1 Apr 2014PD20-10 HAVE ADVANCES IN PATIENT PREPARATION, SURGICAL TECHNIQUES, AND ANTIBIOTIC COATINGS REDUCED INFLATABLE PENILE PROSTHESIS PRIMARY IMPLANTATION INFECTION RATES TO NEARLY ZERO? A LARGE PROSPECTIVE MULTICENTER REGISTRY EXPERIENCE Gerard Henry, Edward Karpman, Bryan Kansas, William Brant, Leroy Jones, Nelson Bennett, Mohit Khera, Tobias Kohler, Andrew Kramer, Brian Christine, Eugene Rhee, and Anthony Bella Gerard HenryGerard Henry More articles by this author , Edward KarpmanEdward Karpman More articles by this author , Bryan KansasBryan Kansas More articles by this author , William BrantWilliam Brant More articles by this author , Leroy JonesLeroy Jones More articles by this author , Nelson BennettNelson Bennett More articles by this author , Mohit KheraMohit Khera More articles by this author , Tobias KohlerTobias Kohler More articles by this author , Andrew KramerAndrew Kramer More articles by this author , Brian ChristineBrian Christine More articles by this author , Eugene RheeEugene Rhee More articles by this author , and Anthony BellaAnthony Bella More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.1700AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail Introduction and Objectives “Prospective Registry of Outcomes with Penile Prosthesis for Erectile Restoration” (PROPPER) is a multi-center clinical registry collecting real-world outcomes for patients with penile implants. PROPPER is designed to document outcomes for American Medical Systems (AMS) 700® and Ambicor® inflatable penile prostheses (IPPs), and Spectra® penile implants. The AMS 700 IPP is impregnated with a combination of rifampin and minocycline (R/M) with several publications showing that it significantly reduces infection rates. ChloraPrep® has been shown to significantly decrease surgical wound site infections as compared to Betadine®. Many of the investigators have a Center of Excellence practice concept. Surgical techniques improvements have made the surgery more efficient and most experienced surgeons try to avoid skin contact with the implant / change gloves more frequently than in the past. We evaluate primary infection rates in patients receiving the AMS 700 R/M IPP. Methods After IRB approval, the PROPPER registry first patients were enrolled in June, 2011. Standardized patient questionnaires and electronic data collection are used to record baseline patient characteristics and surgical implantation details, and to prospectively measure response to treatment annually to five years post-implantation including durability, complications, and effectiveness outcomes. Patients are prospectively followed for significant adverse events including infections. All patients enrolled and consecutively implanted with 3-piece AMS 700 R/M IPPs with completed surgical implantation records were analyzed to quantify device infections in primary implants. Results From June 9, 2011 until September 13, 2013 a total of 466 patients with primary AMS 700 R/M IPPs placed at a total of 12 sites were analyzed. Most devices (416, 89%) were placed by investigators implanting an average of 2 or more patients per month. Surgical approach was penoscrotal for 373 and infrapubic for 92 with 1 other. No (0) infections were reported in any of the 466 patients, after a mean of 14.9 (range: 1.0 - 28.0) months of post-implant follow-up. Conclusions For this large multicenter prospective registry, the short-term follow-up data indicates lower infection rates. High volume implanters utilizing standardized patient preparation, refined surgical technique and antibiotic coated implants appear to have lower infection rates than traditionally published. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e615 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Gerard Henry More articles by this author Edward Karpman More articles by this author Bryan Kansas More articles by this author William Brant More articles by this author Leroy Jones More articles by this author Nelson Bennett More articles by this author Mohit Khera More articles by this author Tobias Kohler More articles by this author Andrew Kramer More articles by this author Brian Christine More articles by this author Eugene Rhee More articles by this author Anthony Bella More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...