PD17-05 TUMOR ANATOMIC COMPLEXITY PREDICTS GROWTH KINETICS OF RENAL MASSES UNDER ACTIVE SURVEILLANCE

Abstract

determined by the MDRD2 equation. Recovery of nephron function (GP/VS 1⁄4 % GFR preserved/% volume saved) would be 100% if all nephrons recovered from the ischemic insult. RESULTS: Median age was 61 years with approximately 50% of patients having open procedures. Median RENAL score was 7. Cold ischemia was used in 50 patients (median 26 min), while 72 had limited warm ischemia (median 20 min). Median %GFR preserved in the operated kidney was 79.5%. Median parenchymal volume saved was 84%. Function in the contralateral kidney remained stable without significant increase. Overall recovery of nephron function (GP/VS) was 95.5%, and was 100.7% for the cold ischemia subgroup and 93% in the limited warm ischemia subgroup. Recovery of nephron function (GP/VS) was similar for all strata of preoperative eGFR in the operated kidney ( 60) as detailed in the table (p > 0.18 for all comparisons), even in the limited warm ischemia subgroup CONCLUSIONS: Preoperative GFR at PN does not correlate with how well the kidney will recover from the ischemia insult. Our results suggest that the amount vascularized parenchyma preserved by the PN is the main determinant of the postoperative GFR. Even poorly functioning kidneys recover well from the ischemic insult as long as limited warm ischemia or hypothermia are utilized.