PD13-04 COMPARISON OF FLOW CHARACTERISTICS OF NOVEL THREE-DIMENSIONALLY PRINTED URETERAL STENTS VS. STANDARD URETERAL STENTS IN A PORCINE MODEL

Abstract

You have accessJournal of UrologyStone Disease: Surgical Therapy I1 Apr 2015PD13-04 COMPARISON OF FLOW CHARACTERISTICS OF NOVEL THREE-DIMENSIONALLY PRINTED URETERAL STENTS VS. STANDARD URETERAL STENTS IN A PORCINE MODEL Zhamshid Okhunov, Michael Del Junco, Renai Yoon, Garen Abedi, Christopher Pulford, Christina Hwang, and Jaime Landman Zhamshid OkhunovZhamshid Okhunov More articles by this author , Michael Del JuncoMichael Del Junco More articles by this author , Renai YoonRenai Yoon More articles by this author , Garen AbediGaren Abedi More articles by this author , Christopher PulfordChristopher Pulford More articles by this author , Christina HwangChristina Hwang More articles by this author , and Jaime LandmanJaime Landman More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1068AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We compared the flow characteristics of novel three-dimensionally (3D) printed ureteral stents to three conventional double-pigtail stents in an ex vivo porcine model. METHODS In 5 ex vivo porcine urinary systems with kidneys and ureters intact we deployed a 5Fr occlusion catheter in an interpolar calyx. We tested each system with antegrade irrigation with 0.9% saline at a pressure of 35 cmH2O before and after stent deployment. We evaluated three standard stents (6Fr Universa® Soft, 7Fr Percuflex™, 7/10Fr Applied Endopyelotomy) and compared them to a 9Fr 3D printed prototype stent. For each stent, we measured the total, extra-luminal, and intra-luminal flow rates. RESULTS The mean total flow rates for 3D printed stents were significantly higher than the 6Fr, 7Fr, and 7/10Fr stents (p<0.001, p=0.003, and p<0.001 respectively). The mean extra-luminal flow rates for the 3D stents were similar to 7Fr stents, but significantly lower than 6Fr stents (p<0.001) and higher than 7/10Fr stents (p<0.001). The mean intra-luminal flow rates for the 3D printed stents were significantly higher than the 6Fr, 7Fr, and 7/10Fr stents (p<0.001, p=0.004, and p<0.001 respectively). CONCLUSIONS In this pilot study, 3D printed stents manifested a mean total flow rates comparable to the flow rates of contemporary stents. Continued advances in technology and material may permit functionally feasible 3D printed ureteral stents. Table 1. Mean Ex-Vivo Flow Measurements (ml/min) for Unstented and Stented Ureters (mean ± SD) Stent Total Flow∗ Extra-luminal Flow Intra-luminal Flow Total Flow as a % of Unstented Ureter Unstented Ureter 4.97 ± 0.062 - - - 6Fr Universa 5.25 ± 0.222 4.41 ± 0.095 4.86 ± 0.090 105.60% 7Fr Percuflex 5.49 ± 0.130 4.01 ± 0.138 5.16 ± 0.057 110.40% 7/10Fr Endopyelotomy 5.18 ± 0.140 2.56 ± 0.309 4.82 ± 0.139 104.20% 9Fr 3D Printed 5.66 ± 0.148 4.00 ± 0.176 5.54 ± 0.293 114.90% ∗ Combined Extra-luminal and Intra-luminal Table 2. Double-Pigtail Stent Dimensions Stent ID (mm) OD (mm) 6Fr 1.33 2.00 7Fr 1.50 2.30 7/10Fr 1.27/1.52 2.30/3.30 9Fr 1.40 3.0 © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e263 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Zhamshid Okhunov More articles by this author Michael Del Junco More articles by this author Renai Yoon More articles by this author Garen Abedi More articles by this author Christopher Pulford More articles by this author Christina Hwang More articles by this author Jaime Landman More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...