PD10-12 WATER II: AQUABLATION THERAPY FOR BENIGN PROSTATIC HYPERPLASIA IN MEN WITH LARGE PROSTATES (80-150CC): 6-MONTH SAFETY AND EFFICACY RESULTS

Abstract

INTRODUCTION AND OBJECTIVES:In a large, blinded, multicenter, randomized trial (WATER) (30-80cc), Aquablation, an ultrasound-guided, robotically executed waterjet ablative procedure demonstrated better outcomes in larger glands compared to TURP. These observations identified the need to assess the safety and efficacy of performing Aquablation in men with larger prostate glands (80-150cc) (WATER II). Herein we report the 6-month outcomes.METHODS:Between September and December 2017, 101 men with moderate-to-severe benign prostatic hyperplasia symptoms and prostate volume of 80-150cc underwent Aquablation in a prospective multicenter international clinical trial. Baseline demographics and standardized postoperative management parameters were carefully recorded in a central independently monitored database. Functional and safety outcomes were assessed at 6 months postoperatively.RESULTS:Mean prostate volume was 107cc (range 80-150). Mean operative time was 37 minutes with a mean Aquablation resection time of ...