PD09-10 SHEAR WAVE ELASTOGRAPHY IN VARICOCELE PATIENTS WITH OLIGO-ASTHENO-TERATOZOOSPERMIA: PROSPECTIVE STUDY TO INVESTIGATE CORRELATION WITH SEMEN PARAMETERS AND HISTOLOGICAL FINDINGS

Abstract

You have accessJournal of UrologyCME1 May 2022PD09-10 SHEAR WAVE ELASTOGRAPHY IN VARICOCELE PATIENTS WITH OLIGO-ASTHENO-TERATOZOOSPERMIA: PROSPECTIVE STUDY TO INVESTIGATE CORRELATION WITH SEMEN PARAMETERS AND HISTOLOGICAL FINDINGS Antonio Luigi Pastore, Andrea Fuschi, Yazan Al Salhi, Alessia Martoccia, Lorenzo Capone, Silvio Scalzo, Paolo Pietro Suraci, Onofrio Antonio Rera, Fabio Maria Valenzi, Alice Antonioni, and Antonio Carbone Antonio Luigi PastoreAntonio Luigi Pastore More articles by this author , Andrea FuschiAndrea Fuschi More articles by this author , Yazan Al SalhiYazan Al Salhi More articles by this author , Alessia MartocciaAlessia Martoccia More articles by this author , Lorenzo CaponeLorenzo Capone More articles by this author , Silvio ScalzoSilvio Scalzo More articles by this author , Paolo Pietro SuraciPaolo Pietro Suraci More articles by this author , Onofrio Antonio ReraOnofrio Antonio Rera More articles by this author , Fabio Maria ValenziFabio Maria Valenzi More articles by this author , Alice AntonioniAlice Antonioni More articles by this author , and Antonio CarboneAntonio Carbone More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002535.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Shear wave elastosonography (SWE) is a non-invasive ultrasound imaging modality used to assess the mechanical properties of tissues such as rigidity and elasticity. In this prospective study, we investigated the effect of laparoscopic varicocelectomy on the elasticity, degree of fibrosis and function of the testes through SWE and we evaluated the correlation with semen parameters and histology findings. METHODS: Male patients with monolateral left varicocele and progressive alteration of the semen quality suggestive for oligo astheno teratozoospermia (OAT) were enrolled in this prospective study. Patients were evaluated before varicocelectomy, 3 and 6 months after surgery with semen analysis, ecocolordoppler US and SWE. In all patients, a left testicular biopsy was performed at the time of varicocelectomy, and it was repeated after 6 months in 55% of patients in order to investigate the histological findings and to correlate with SWE results. RESULTS: The study was conducted on 82 patients with varicocele and OAT. SWE showed a statistically significant difference between left and right testicles. Three months after surgery the mean left testicular volume increased, mean left SWE features decreased, and sperm count increased (p <.0001). The SWE parameters, testicular volume and semen analysis values showed a statistically significant positive correlation between the pre and postoperative results (p <.0001). The histological alterations were significantly changed 6 months postoperative with a complete morphology recovery in accordance with SWE results. CONCLUSIONS: SWE showed a statistically significant positive correlation with testicular volume, semen analysis and histological findings. This study represents the first investigation that correlates the varicocele, the testis volume, the quality of the seminal fluid ant the histological findings with the ultrasound and SWE values. Source of Funding: None © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e181 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Antonio Luigi Pastore More articles by this author Andrea Fuschi More articles by this author Yazan Al Salhi More articles by this author Alessia Martoccia More articles by this author Lorenzo Capone More articles by this author Silvio Scalzo More articles by this author Paolo Pietro Suraci More articles by this author Onofrio Antonio Rera More articles by this author Fabio Maria Valenzi More articles by this author Alice Antonioni More articles by this author Antonio Carbone More articles by this author Expand All Advertisement PDF DownloadLoading ...