PD07-10 EFFECT OF BARIATRIC SURGERY ON SEMEN PARAMETERS AND HORMONE PROFILE; A PROSPECTIVE OBSERVATIONAL STUDY.

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You have accessJournal of UrologyInfertility: Therapy II1 Apr 2016PD07-10 EFFECT OF BARIATRIC SURGERY ON SEMEN PARAMETERS AND HORMONE PROFILE; A PROSPECTIVE OBSERVATIONAL STUDY. Ahmad Majzoub, Mohamed Arafa, Sami Al Said, Gaby Jabbour, Moataz Basha, Edmund Sabanegh, and Haitham El Bardisi Ahmad MajzoubAhmad Majzoub More articles by this author , Mohamed ArafaMohamed Arafa More articles by this author , Sami Al SaidSami Al Said More articles by this author , Gaby JabbourGaby Jabbour More articles by this author , Moataz BashaMoataz Basha More articles by this author , Edmund SabaneghEdmund Sabanegh More articles by this author , and Haitham El BardisiHaitham El Bardisi More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2813AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Obesity has become a major health concern with a prevalence rate approaching epidemic states. An inverse relationship between men′s body weight and semen parameters have been observed suggesting a favorable role for weight loss in improving fertility. Bariatric surgery is currently considered the most reliable approach to weight loss in morbidly obese patients. This is considered to be the largest study in determining changes in semen analyses and hormone levels in men before and after bariatric surgery. METHODS This is a prospective study of patients undergoing bariatric surgery (Sleeve Gastrectomy), who were investigated with semen analysis and serum hormone tests before and 9-12 months after surgery. Changes in patients weight and body mass index (BMI) were tracked throughout the study period. Patients were divided into three groups according to their initial sperm (Sp) count; azoospermia, oligospermia and normal count group. The median loss of BMI was used as a cutoff to further classify patients according to extent of weight loss. RESULTS Fifty patients were invited to participate in this study. Four lost follow up and were excluded. The patients’ preoperative seminal investigations revealed azoospermia in 13 (28.3%), oligospermia in 19 (41.3%) and normal Sp count in 14 (30.4%) (Table 1). Overall, a statistically significant increase in serum testosterone (T) was observed after surgery (p=0.001)(Table 2). Between study groups, the percentage improvement of Sp count was statistically significant in oligospermic men only, while that of serum T was statistically significant in all groups (Figure 1). The extent of weight loss does not appear to significantly affect Sp count and serum T percentage improvement (Figure 2). CONCLUSIONS Weight loss appears to have a favourable effect on sperm count and serum testosterone. The effect on sperm count is most notable in oligospermic men. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e226-e227 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Ahmad Majzoub More articles by this author Mohamed Arafa More articles by this author Sami Al Said More articles by this author Gaby Jabbour More articles by this author Moataz Basha More articles by this author Edmund Sabanegh More articles by this author Haitham El Bardisi More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...