PD06-07 GLEASON SCORE WITHIN PROSTATE ABNORMAL AREAS DEFINED BY MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING DID NOT VARIED ACCORDING TO THE PIRADS SCORE.

Abstract

You have accessJournal of UrologyImaging/Radiology: Uroradiology II1 Apr 2016PD06-07 GLEASON SCORE WITHIN PROSTATE ABNORMAL AREAS DEFINED BY MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING DID NOT VARIED ACCORDING TO THE PIRADS SCORE. Hakim Slaoui, Yann Neuzillet, Mathieu Rouanne, Abdelali Abdou, Pierre Marie Lugagne Delpon, Antoine Scherrer, Camelia Radulescu, Vincent Molinié, and Thierry Lebret Hakim SlaouiHakim Slaoui More articles by this author , Yann NeuzilletYann Neuzillet More articles by this author , Mathieu RouanneMathieu Rouanne More articles by this author , Abdelali AbdouAbdelali Abdou More articles by this author , Pierre Marie Lugagne DelponPierre Marie Lugagne Delpon More articles by this author , Antoine ScherrerAntoine Scherrer More articles by this author , Camelia RadulescuCamelia Radulescu More articles by this author , Vincent MoliniéVincent Molinié More articles by this author , and Thierry LebretThierry Lebret More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2627AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Multiparametric magnetic resonance imaging (mpMRI) has been used to assess prostate cancer (PCa) aggressiveness. Subsequently, MRI-targeted biopsy was used to improve the accuracy of PCa diagnosis. Hence, we aim to correlate mpMRI of the prostate reporting (PIRADS v2) with the Gleason score into both radical prostatectomy specimen, and MRI-targeted biopsies. METHODS mpMRI of 74 patients who underwent a radical prostatectomy (RP) after mpMRI guided biopsy (UroStation, Koelis, Grenoble, France) performed in our academic centre were retrospectively reviewed by a senior radiologist. Abnormal mpIMR zone were defined as PIRADS score =3, 4, or 5. Then corresponding tissue was reviewed into RP by a senior pathologist. The Gleason score distribution was compared according to the PIRADS score using Fisher's Exact Test. Results were compared to mpMRI guided biopsy of the same anatomical zone. Cohen's kappa concordance test was used to compare biopsies and prostatectomy specimen analyses. RESULTS The Gleason score distribution within target in RP specimen according to the PIRADS score was reported in Table 1. This distribution was similar in the three PIRADS score groups (p= 0.13). In 3 cases, MRI-targeted biopsy found no cancer. There are a fair agreement between Gleason score within MRI-targeted biopsy and within target in RP specimen (Kappa coefficient = 0.378, CI95% [0.194-0.563]) (Table 2). CONCLUSIONS In the present study, PIRADS score was not associated with signicative differences regarding Gleason score distribution within target. Moreover, concordance of Gleason score in MRI-targeted biopsy with those within target in RP specimen was weak. Information supplied to patients should be consistent with this. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e176-e177 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Hakim Slaoui More articles by this author Yann Neuzillet More articles by this author Mathieu Rouanne More articles by this author Abdelali Abdou More articles by this author Pierre Marie Lugagne Delpon More articles by this author Antoine Scherrer More articles by this author Camelia Radulescu More articles by this author Vincent Molinié More articles by this author Thierry Lebret More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...