PD03-09 QUALITY CONTROL INDICATORS (QCIS) FOR TRANSURETHRAL RESECTIONS OF BLADDER TUMORS: CORRELATION OF QCIS WITH CLINICAL OUTCOME IN A BELGIAN MULTI-CENTER PROSPECTIVE REGISTRY

Abstract

You have accessJournal of UrologyBladder Cancer: Non-invasive I (PD03)1 Apr 2020PD03-09 QUALITY CONTROL INDICATORS (QCIS) FOR TRANSURETHRAL RESECTIONS OF BLADDER TUMORS: CORRELATION OF QCIS WITH CLINICAL OUTCOME IN A BELGIAN MULTI-CENTER PROSPECTIVE REGISTRY Tim Muilwijk*, Murat Akand, Yannic Raskin, Cedric Jorissen, Lorenz Vanhoucke, Kathy Vander Eeckt, Siska Van Bruwaene, Ben Van Cleynenbreugel, Steven Joniau, and Frank Van Der Aa Tim Muilwijk*Tim Muilwijk* More articles by this author , Murat AkandMurat Akand More articles by this author , Yannic RaskinYannic Raskin More articles by this author , Cedric JorissenCedric Jorissen More articles by this author , Lorenz VanhouckeLorenz Vanhoucke More articles by this author , Kathy Vander EecktKathy Vander Eeckt More articles by this author , Siska Van BruwaeneSiska Van Bruwaene More articles by this author , Ben Van CleynenbreugelBen Van Cleynenbreugel More articles by this author , Steven JoniauSteven Joniau More articles by this author , and Frank Van Der AaFrank Van Der Aa More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000823.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Quality control indicators (QCIs) can objectively evaluate guideline adherence. We assessed 6 QCIs, based on guideline recommendations, in the treatment of NMIBC using a prospective transurethral resection of bladder tumor (TURBT) registry in 3 Belgian centers and assessed whether these QCIs correlated with clinical outcome of patients. METHODS: TURBT procedures were collected using electronic case report forms (eCRFs) in a prospective TURBT registry in 3 centers between 06-2013 and 03-2017. Outcomes of interest were recurrence-free survival (RFS), overall survival (OS), and cystectomy-free survival (CFS). Six QCIs were assessed for their indication: complete resection status (CRS), repeat resection (re-TUR), presence of detrusor muscle (DM) in the resection specimen, single post-operative instillation of Mitomycin C (MMC), adjuvant intravesical instillation of BCG, and initial therapy ≤6 weeks after diagnosis. Kaplan-Meier plots were used for visualization of outcome data and log-rank to compare clinical outcome for each QCI. RESULTS: A total of 1350 TURBTs were collected, 1165 TURBTs met inclusion criteria for a total of 907 patients. Median follow up was 21.8 mo (IQR: 12.1-34.3). RFS, OS, and CFS at 4-year were 63.5% (95%CI: 59.7-67.5), 78.9% (95%CI: 75.2-82.8), and 93.1% (95%CI: 91.4-94.9) respectively. Scores on QCI were: CRS: 97.1%, re-TUR: 33.6%, DM: 45.8%, MMC: 69.6%, BCG: 39.6%, and timing ≤6 weeks 87.7%. The following QCIs had a significant impact on outcome: CRS on OS, and CFS; re-TUR on OS (Figure 1A), and CFS; MMC on RFS (Figure 1B); BCG on RFS (Figure 1C), and OS (Figure 1D). CONCLUSIONS: We demonstrate that we can assess QCIs (based onguideline recommendations) using a Belgian prospective multicenter TURBT registry. Furthermore, we demonstrate that the following QCIs were correlated with clinical outcome of patients: CRS, re-TUR, MMC, and BCG. Therefore, QCIs could be used to check guideline adherence, and allow for comparison between centers, with the ultimate goal of increasing guideline adherence. Source of Funding: NA © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e75-e75 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Tim Muilwijk* More articles by this author Murat Akand More articles by this author Yannic Raskin More articles by this author Cedric Jorissen More articles by this author Lorenz Vanhoucke More articles by this author Kathy Vander Eeckt More articles by this author Siska Van Bruwaene More articles by this author Ben Van Cleynenbreugel More articles by this author Steven Joniau More articles by this author Frank Van Der Aa More articles by this author Expand All Advertisement PDF downloadLoading ...