Abstract
The palladium-catalyzed cross-coupling carbonyl insertion reaction between 3,7-bis(N,N-dimethylamino)-10H-dibenz[b,e]iodinium iodide (1) and alcohols or amines 2 is described. Some new amides and esters 3 containing an active iodo functional group have been prepared in 65-91% yields.
Highlights
In the past few decades, much attention has been focused on palladium-catalyzed carbonylation reactions [1,2], which provide a simple method for synthesizing some complicated compounds [3,4,5,6]
The new compounds obtained by carbonyl insertion still have an active iodo functional group, which can serve for the intermediate to undergo further reactions
We examined the influences of catalyst, base and reaction time on this reaction through the cross-coupling of 1 with alcohols
Summary
In the past few decades, much attention has been focused on palladium-catalyzed carbonylation reactions [1,2], which provide a simple method for synthesizing some complicated compounds [3,4,5,6]. We will describe such a palladium-catalyzed cross– coupling carbonylative insertion reaction between an iodoheterocyclic compound and alcohols or amines.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
