Abstract
Biliary obstruction can arise in patients with unresectable pancreatic cancer (UPC), which leads to delayed initiation of chemotherapy (CTx). Biliary drainage (BD) is essential for these patients, however, re-obstruction could be frequently observed after BD and impair maintenance of CTx. Whereas, we have no established data comparing prognosis between BD and non-BD patients. Also, there has been no data comparing efficacy between first-line FOLFININOX (FFX) or Gemcitabine plus nab-PTX (GnP) after BD.
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