Abstract

Background: Several prognostic variables determine survival after resection of colorectal liver metastasis (CRLM). These prognostic factors are included in clinical risk scores (CRS), which are used to predict outcome. Fong's CRS (1999) is the most widely used and validated. It includes lymph node status of the primary tumor as a prognostic factor. Since its introduction however, the use of adjuvant chemotherapy in node positive colon cancer patients has improved survival significantly. Furthermore, the TME (total mesorectal excision) technique and the use of neoadjuvant radiotherapy for rectal cancer has improved outcomes in these patients.

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