PCV63 IMPACT OF DEPRESSION ON HEALTH-RELATED QUALITY OF LIFE AMONG OLDER ADULTS WITH MYOCARDIAL INFARCTION IN THE UNITED STATES

Abstract

We assessed the effect of depression on health-related quality of life (HRQoL) among myocardial infarction (MI) survivors in the United States (US). Using the 2015 Behavioral Risk Factor Surveillance System (BRFSS) data, our final study sample consisted of MI survivors (identified by “yes” response to the question: “Has a doctor, nurse, or other health care professional ever told you that you had a heart attack, also called a myocardial infarction?”) aged 50 years and older, who completed the BRFSS survey. Depression was identified using a similar question. Our dependent variable (HRQoL) comprised of number of days physical health and mental health was poor during the past 30 days; activity limitations present (yes/no); received recommended sleep (yes/no); how often emotional support received (always/usually, sometimes, or rarely/never); life satisfaction (very satisfied/satisfied or dissatisfied/very dissatisfied); and perceived general health (excellent/very good, good, or fair/poor). We conducted multivariable binomial and multinomial logistic regression analyses examining the association of presence/absence of depression on HRQoL after adjusting for demographic, socioeconomic and other health variables (a-priori alpha=0.05). Our final study sample consisted of 20,483 adults with MI among whom 5,343 (26.19%) reported having depression. MI survivors with depression were more likely to report fair/poor general health, limitations in activity, dissatisfaction with life, and more poor mental and physical health days compared to those without depression. For example: MI survivors with depression reported 2.7 times more (Adjusted Odds Ratio: 2.65: 95% Confidence Interval 2.06-3.45; p<0.0001) fair/poor perceived general health than MI survivors without depression. There was no difference in level of emotional support or sleep quality. In this US nationally representative data, MI survivors with depression had poorer HRQoL compared to MI survivors without depression. These findings underline the need for developing appropriate supportive care for MI survivors with depression.