Abstract
Globally, esophageal cancer (EC) ranks 7th in cancer incidence and 6th in cancer-related mortality. A 5-year survival of 3% for stage IV patients reflects poor prognosis and places significant burden on patient lives. A systematic literature review (SLR) was conducted to characterize the humanistic burden using health-related quality of life (HRQoL) outcomes and health utilities in advanced/metastatic esophageal cancer (EC) patients and evaluate evidence gaps.
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