Abstract
Leber’s Hereditary Optic Neuropathy (LHON) is a rare, maternally inherited mitochondrial disease, causing central vision loss due to optic neuropathy. LHON typically emerges in young adults and is more common among men. Symptoms start with painless blurring of the central vision, usually in one eye at first, that rapidly progresses to blindness in both eyes. The impact of sudden vision loss on patients’ quality of life and wellbeing is not well documented. The present study used quantitative and qualitative methods to characterise the burden of LHON at different levels of visual acuity.
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