Abstract
The core component of the PCR(Polymerase Chain Reaction)instrument is the temperature control system. The PCR reaction process also has high requirements for temperature control. At present, the most widely used PID temperature control system has been difficult to adapt to the high efficiency and high precision requirements of the PCR instrument. In this paper, the mathematical model of TEC(Thermo Electric Cooler) based PCR instrument is deduced, and the multi-modal control system of PCR instrument is designed by using multi-modal control idea combined with fuzzy control and fuzzy PID control. Compared with the traditional PID temperature control, the system has a short steady-state time, a small overshoot and a strong robustness. Based on the temperature control system, the PCR reaction cycle can be shortened and the system accuracy can be increased.
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