PCN142 - An Overview of Domestic Cancer Drugs in Turkey: 2008-2012

Abstract

PCN142 AN OVERVIEW OF DOMESTIC CANCER DRUGS IN TURKEY: 2008-2012 Vural E.H., Safak Yilmaz E., Vural I.M., Dogan E, Akbulat A., Gursoz H., Kerman S. Turkish Medicines and Medical Devices Agency, Ankara, Turkey OBJECTIVES: Cancer is among the most common causes of death in Turkey. Cancer diagnosis and treatment management were substantially improved by the Ministry of Health. Generic market and price movements of different kinds of drug groups show different characteristics. In this study we aimed to demonstrate the impact of domestic manufacture of cancer drugs on import cancer drug sales in Turkey in terms of both boxes and cost sale trend analysis between 2008 and 2012. METHODS: This study was designed as an observational, retrospective study. Domestic oncology drugs were chosen from the base oncology drug groups. The sales data of the domestic oncology drugs and both original and generic import drugs which have the same active ingredient with the domestic drugs was obtained from the Information Medical Statistics (IMS) database from September 2007 to July 2012. Sales data is evaluated with segmented regression analysis for interrupted time series. RESULTS: Oncology drug sales report showed that the market share of domestic products increased approximately 38% at 2012 from 0,5% at 2008. Before the cut point, there was a statistically significant increase in the sales level of import oncology drugs, but after the cut point sales trend showed a statistically significant decrease. Import oncology drugs’ unit price per box decreased from 196.5TL between September 2007 and October 2008 to 172.6TL between November 2008 and July 2012. But domestic oncology drugs’ unit price per box was 91.8TL between November 2008 and July 2012. CONCLUSIONS: In conclusion, domestic drug manufacturing has important contributions to a country’s economy including low drug prices, supplying for the domestic consumption, creation of employment opportunities and also as export potentials. Price cut in 2009 and 2011 in Turkey and “Reference Pricing System” should be taken into consideration for this price change evaluation in the case of domestic product manufacturing.