Abstract
Dioxin exhibits serious health effects when it reaches as concentration a few ppt in human body fat. Dioxin is a powerful hormone disrupting chemical. By binding to a cell's hormone receptor, it literally modifies the functioning and genetic mechanism of the cell, causing a wide range of effects, from cancer to reduced immunity, nervous system disorders, miscarriages and birth deformity. Median i-TEQ in adipose tissue of the BienHoa residents is comparable with that of the developed countries while mean i-TEQ of the Bien Hoa residents is higher in both groups, especially older people group. This group has some exceptional cases with i-TEQ value up to 1148.7pg/g. The i-TEQ value in our studies is higher than that conducted by other studies. However, our result supports a conclusion: at present, the dioxin concentration in natural environment and human bodies in Southern Vietnam is only a residue and not higher than that in developed countries.
Highlights
Based on the published researches of many scientists (Cau HD, 2003), the strong toxicity of dioxin that after penetrating into the human body, generates several notorious features on congenital anomalies for F1 generation of those who were exposed to A.O/Dioxin
Human adipose tissue is an important matrix to understand the influence of dioxins on human health
The PCDD/Fs concentration based on i
Summary
Based on the published researches of many scientists (Cau HD, 2003) , the strong toxicity of dioxin that after penetrating into the human body, generates several notorious features on congenital anomalies for F1 generation of those who were exposed to A.O/Dioxin. Human adipose tissue is an important matrix to understand the influence of dioxins on human health (especially adipose tissue of pregnant women because it is directly related to reproduction and generation). Because the PCDD/Fs are lipophilic compounds, when they penetrate into human body via direct/indirect contact they accumulate mainly in human body with high lipid content. Their concentration in human tissue is very important factor to evaluate the critical toxic level for human health and for risk assessment. The samples were pre-treated and analyzed in Cecotox Lab and intertested in Carso Lab (Laboratoire Santé Environnement et Hygiène de Lyon – a certified lab on dioxin analysis in France).
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