Abstract
Background: Effective vaccines are most powerful armamentariums in our fight against global COVID-19 pandemic. Based on available literature, the benefits of vaccination significantly outweigh the low risk of blood clots and other hematological complications reported following vaccination. Here we are reporting 6 such rare complications of COVID immunization which was happened within 4days -42days following vaccination. Aims: we aimed to study the rare hematological adverse events follwoing the COVID vaccination Methods: Here we are reporting six cases presented to our institute following COVID vaccination within 4 weeks following vaccination, data were retrieved from MRD and events and outcomes were tabulated. Results: - S.No AgeYrs. Sex Vaccine type COVID infection Presentation Time between Vaccination and effect Treatment Outcome 1 62 M Covishield No Severe aplastic anemia(SAA) 17days ATG+CSA+Elthrombopag EBV HLHAlive 2 44 F Covishield No SAA 24days ATG+CSA+Elthrombopag Portal vein thrombosisAlive 3 62 F Covishield No SAA 42days ATG+CSA+Elthrombopag Died,Fungal pneumonia 4 64 F Covishield No ITP(Immune mediated thrombocytopenia) 18days Steroids Complete response,Alive 5 82 F Covishield No ITP 26days Steroids Complete response,Alive 6 69 F Covishield No ITP 28days IVIg, SteroidsRomiplastim Complete response,Alive Summary/Conclusion: Hematological complications commonly reported following COVID-19 vaccination were thrombosis with thrombocytopenia syndrome following AstraZeneca vaccination. However for severe aplastic anemia literature was scanty and hardly any reports in the literature search.In our paper we reported three severe aplastic anemia and 3 Immune thrombocytopenic Purpura following Astrazenca vaccination. Need high index of suspicion and Bone marrow examination required to confirm the underlying entity appropriately.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
