Abstract
Increasing evidence supports vacuum-assisted biopsy (VAB) instead of surgical excision for the management of lesions of uncertain malignant potential (B3). This followed reports of up to 34% upgrade to malignancy on excision. In January 2012, regional guidance was adopted to clarify the options for managing such lesions. In our department, we have used similar local guidelines since 2011. We report our analysis of the management of B3 lesions before and after the introduction of VAB.
Highlights
Previous research in this centre enabled the introduction of a local protocol of nonbiopsy and discharge of women
Mammography-detected cancers were luminal in 77% (P = 0.03), node negative in 77% (P = 0.005), with ductal carcinoma in situ (DCIS) in 81% (P = 0.007)
We applied our approach to 13 experienced readers assessing 13,694 screening mammograms from a large clinical study where women are categorised as high risk if they have a 5 to 8% 10-year risk computed by a validated risk model and their breast density is in the top decile of the study population
Summary
Previous research in this centre enabled the introduction of a local protocol of nonbiopsy and discharge of women
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
