Pauson-Khand approach to chiral, diastereomerically pure group 4 ansa-metallocene complexes

Abstract

The C 2-symmetric bis(1,6-enynes) threo-1,10-diphenyl-5,6-divinyl-1,9-decadiyne and threo-9,10-divinyl-5,13-octadecadiyne undergo the intramolecular Pauson-Khand reaction regio- and stereoselectively to give C 2-symmetric bis(enones) with two bicyclo[3.3.0]octyl moieties joined at the C6 position. Experiments aimed at converting the bis(enones) into chiral, diastereopure ansa-bridged group 4 metallocene complexes are described.