Abstract
The paucicellular variant of Anaplastic carcinoma of thyroid (ANTC) is an uncommon entity. It can pose diagnostic difficulty both in cytology and histology. Its recognition is important as it has an aggressive clinical course with poor outcome. We report here a forty two year old female patient who presented with a midline neck swelling and painful deglutition of three months duration. A diagnosis of subacute thyroiditis was entertained clinically and on initial cytologic evaluation. The subsequent frozen and paraffin section diagnosis considered was Riedei's thyroiditis. Patient's rapid clinical course and fatal outcome necessitated a review which led to the recognition of ANTC-paucicellular variant. Because of the paucicellular nature of the lesion, this variant is likely to be underdiagnosed in aspiration cytology. The clue to recognising it in histology lies in paying attention to the areas of cellularity, atypical cells and the infarcioid type of necrosis; features not associated with Riedei's thyroiditis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.