Abstract

Knee osteoarthritis (OA) manifests with pain, joint stiffness, and limited function. In traditional Chinese medicine, knee OA is differentiated into three patterns: yang deficiency and cold coagulation, kidney deficiency, and blood stasis. The objective of this study was to determine whether yang deficiency cold coagulation patients respond better to thermal laser acupuncture treatment than do non-yang deficient patients. Fifty-two patients with OA were allocated to group A (yang deficient, n = 26) or B (non-yang deficient, n = 26). All patients received a 20-min thermal laser acupuncture treatment at acupoint Dubi (ST 35) three times a week for two weeks and twice a week for another four weeks. Outcome assessments were performed immediately after the first treatment, and at weeks 2, 6, and 10. Group A function scores were significantly better than those of Group B at weeks 2 (P = 0.049), 6 (P = 0.046), and 10 (P = 0.042), but no significant differences were found between the two groups in pain and stiffness scores at any time point. No significant adverse effect was observed. The combined 10.6 μm–650 nm laser treatment might be most beneficial to yang deficiency cold coagulation knee OA patients, particularly in improving function.

Highlights

  • Osteoarthritis (OA) manifests clinically as chronic joint pain, stiffness, and swelling accompanied by dysfunction

  • The study was conducted from July 2007 to February 2009 in out-patient settings at two research centers in Shanghai, China: Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine and First People’s Hospital affiliated to Shanghai Jiao Tong University

  • The research protocol was approved by the Institutional Review Board of Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine

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Summary

Introduction

Osteoarthritis (OA) manifests clinically as chronic joint pain, stiffness, and swelling accompanied by dysfunction. The incidence of the disease tends to increase, and pain and dysfunction of the knee can seriously affect life activities [2, 3]. Conventional therapies, usually NSAIDs, mainly are used to manage symptoms such as joint pain, improve function, delay the progression of joint damage, and improve patient quality of life [5]. These often have undesirable side effects such as gastrointestinal disorders, making treatment unsustainable [6]

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