Abstract

Insecticide resistance due to mutations in the knockdown resistance (kdr) gene in Anopheles gambiae populations has been reported in some West African countries, despite the absence of large-scale mosquito control in this sub-region. Agricultural and/or household use of insecticides has been implicated in the development of resistance in An. gambiae. However, such studies had not been carried out in Ghana, where large-scale use of insecticide-treated bed nets is a major component of the Roll Back Malaria programme. There is therefore a need to establish baseline information on patterns of insecticide use and vector susceptibility levels in Ghana. A questionnaire survey of 171 households with 800 inhabitants was conducted to obtain information on knowledge, attitude and perception of respondents on household insecticide use in the Accra metropolis. Also, adult An. gambiae were tested for resistance to permethrin and deltamethrin using WHO adult mosquito test kits. The polymerase chain reaction (PCR) was us...

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