Abstract

Body-shape change is a major concern for many patients with HIV infection. However, exactly what alterations in fat distribution occur during the course of HIV infection, and the roles of host-, viral-, and treatment-related factors in the loss or accumulation of regional fat, remain unclear. The Fat Redistribution and Metabolic Change in HIV Infection (FRAM) study was a large, cross-sectional comparison of body shape between HIV-infected patients and control subjects from the general population. Both …

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