Abstract
PurposeUveitis is the third leading cause of blindness worldwide. This study aimed to summarize the pattern of uveitis in Iran through a systematic review.MethodsThis review was conducted according to the guidelines for systematic reviews in the following four steps: literature search, study selection and assessment, inclusion and exclusion criteria, and statistical analysis.Results One hundred and fifteen articles were identified by an encyclopedic literature search, and three independent investigators examined them according to the defined inclusion and exclusion criteria. Eventually, 109 manuscripts were retrieved and six cross-sectional studies covering 3,567 patients were included and reviewed. According to the results, the mean age of patients was 40 years, and sex was not a statistically significant predisposing factor. The most common anatomical pattern of involvement was anterior uveitis, and the prevalence of the other three types of uveitis, including middle, posterior, and pan-uveitis, were almost equal. Overall, the most common etiologies of uveitis in the Iranian population were idiopathic uveitis, toxoplasmosis, Behcet's syndrome, and Fuchs heterochromic iridocyclitis.ConclusionThis study depicted the pattern of uveitis in the Iranian society; this can help physicians in the diagnostic approach, management, and treatment of patients.
Highlights
We review all the available articles on the epidemiology of uveitis in Iran to discuss novel and interesting data regarding the pattern of the disease
Of the nine studies that examined the epidemiology of uveitis in the Iranian society, three were excluded because two were duplicates[32, 33] and one was conducted only in patients with posterior uveitis.[34]
Based on the extensive literature review, to the best of our knowledge, no study has reported the epidemiological pattern of uveitis in the general Iranian population, and no study has been conducted in the field of general ophthalmology
Summary
Uveitis is an umbrella term that includes a wide spectrum of intraocular inflammatory conditions in which the various parts of the eye may be attacked by the immune system.[1]. Uveitis refers to inflammation of the uveal tract (iris, ciliary body, and choroid); retina, vitreous body, optic nerve, and sclera may be involved.[2]. The etiology of the disease is categorized into traumatic, infectious, and noninfectious-immunologic causes and masquerade syndromes.[3, 4].
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