Abstract

Coronary artery disease is one of the l wide. lipoprotein(a) [Lp (a)] is a cholesterol rich plasma lipoprotein Its structure and composition closely resembles low density lipoproteins (LDL). Elevated Lp (a) is the most common familial lipoprotein disorder in patients with premature Coronary Artery Disease (CAD). Objective: To study the pattern of plasma LP(a) levels in Sudanese patients who presented with coronary artery disease [CAD]. Material and Methods: This is a case control study. 30 patients randomly se admitted to the coronary care unit [C.C.U] in Elshaab Teaching Hospital with acute coronary syndrome in the period from April 2004 to July 2005 while 30 patients with non ischaemic cardiac problems admitted to the same ho randomly selected as a matched control group. Serum LP(a), cholesterol and low C) concentrations were determined using the conventional enzymatic colorimetric methods. Results: LP(a), cholesterol and LDL lev respectively]. Lp(a) is also high in patients blew 60years of age. High LP(a) correlates with high cholesterol, LDL and other risk factors. The role of Lp(a) as an independent 15 patients with no other risk factors had high LP(a) level. Conclusion: This study demonstrated significant Lp(a) level in patients with other risk factors of CAD [including cholesterol and LDL].

Highlights

  • Coronary artery disease [CAD] is one theThis study had determined the pattern of leading causes of death for both men and women plasma Lp(a) in Sudanese patients who presented world wide[1]

  • Lipoprotein a [Lp (a)] is a cholesterol rich in the period April 2004 to July 2005 while 30 plasma lipoprotein which was first identified as patients with non ischaemic cardiac problems plasma antigen in 1963 by Berg 4

  • This study demonstrated significant high levels of Lp(a) in Sudanese patients with CAD and showed positive correlation between Lp(a) and the other risk factors which is in keeping with the multi factorial etiology of CAD11

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Summary

Introduction

Coronary artery disease [CAD] is one theThis study had determined the pattern of leading causes of death for both men and women plasma Lp(a) in Sudanese patients who presented world wide[1]. Coronary artery disease [CAD] is one the. CAD risk increases with age, obesity with coronary artery disease CAD and certain diseases such as diabetes, Material and methods hypertension, high serum cholesterol level, high. The study level of low-density lipoprotein (LDL) in the group [group I] included 30 patients randomly blood and with certain social habits such as selected from a pool of 624 patients admitted to smoking[2]. Its structure and admitted to the same hospital were randomly composition closely resemble low density selected as a matched control group [group II]

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