Abstract
Total 60 patients were selected as per described criteria from the department of Otolaryngology and head neck surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from January 2005 to October 2006. In this study of 60 patients of differentiated thyroid carcinoma (DTC), majority of the patients are within 31-50 yrs age group with female predominance. Papillary carcinoma was more common in 31-40 yrs age group and follicular carcinoma was more common in 41-50 years. Thyroid swelling was the most common presenting symptom of DTC (91.66%), followed by cervical lymphadenopathy (33.33%). Among the 60 DTC patients, papillary carcinoma was commoner (73.33%) than follicular carcinoma (26.67%). Overall female-male ratio for these 60 patients of DTC was 1.72: 1, but in papillary type the ratio was 1.44:1. and for follicular carcinoma was 3:1. Out of 44 papillary carcinoma patients 18 patients had cervical lymph node metastasis (40.90%), and out of 16 follicular carcinoma patients 2 had cervical lymph node metastasis (12.50%); P < 0.05. Among the 44 papillary carcinoma patients only 1 had distant metastasis (2.27%), and among the 16 follicular carcinoma patients 4 had distant metastasis (25%); P <0.05. 85% of the patients were presented with unilateral and 15% were presented with bilateral lymph node metastasis. In this series, distant metastasis was found in bone and lung, Maximum lymph node metastasis was found in level II (42.10%), level III (57.89%) and level IV (42.10%). Finally the Chi-square (x2) significance test was performed according to above described findings and it was found that there is significant difference in the pattern of lymph node metastasis and of distant metastasis between papillary and follicular type of DTC (P<0.05). Key words: Thyroid carcinoma; Metastasis. DOI: 10.3329/bjo.v15i2.5059 Bangladesh J Otorhinolaryngol 2009; 15(2): 60-68
Highlights
Recognized thyroid carcinoma constitutes less than 1% of human malignant tumours 1
Papillary thyroid carcinoma (PTC) type is more frequent in 31-40 years. age group (36.37%) followed by Follicular thyroid carcinoma (FTC) type which is more frequent in 41-50 years. age group (37.50%)
In a series of differentiated thyroid carcinoma (DTC) cases in Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka it has been shown that the incidence of DTC is increasing, like 3 cases in 1985 to 23 cases in 2000 1.The cause this may be due to modern diagnostic techniques and increased cancer consciousness among the people
Summary
Recognized thyroid carcinoma constitutes less than 1% of human malignant tumours 1. Among them differentiated thyroid carcinoma is the most common variety. There are two types of differentiated thyroid carcinoma. The incidence of thyroid carcinoma varies in different series[2]. The presence of a solitary thyroid nodule is a risk factor for malignancy. The incidence of malignancy within a solitary thyroid nodule is approximately 10%3. The reported incidence of carcinoma in solitary nodule
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